BioXtal, Speeding up your discoveries. From DNA to 3D structure.


Structural biology field:

(1)H, (13)C and (15)N assignment of the GNA1946 outer membrane lipoprotein from Neisseria meningitidis.
Neumoin A, Leonchiks A, Petit P, Vuillard L, Pizza M, Soriani M, Boelens R, Bonvin AM.
Biomol NMR Assign. 2010 Dec 28.

Exploiting antigenic diversity for vaccine design: the chlamydia ArtJ paradigm.
Soriani M, Petit P, Grifantini R, Petracca R, Gancitano G, Frigimelica E, Nardelli F, Garcia C, Spinelli S, Scarabelli G, Fiorucci S, Affentranger R, Ferrer-Navarro M, Zacharias M, Colombo G, Vuillard L, Daura X, Grandi G.
J Biol Chem. 2010 Sep 24;285(39):30126-38

Membrane receptor field:

Mammalian G protein-coupled receptor expression in Escherichia coli: II. Refolding and biophysical characterization of mouse cannabinoid receptor 1 and human parathyroid hormone receptor 1.
Michalke K, Huyghe C, Lichière J, Gravière ME, Siponen M, Sciara G, Lepaul I, Wagner R, Magg C, Rudolph R, Cambillau C, Desmyter A.
Anal Biochem. 2010 Jun 1;401(1):74-80. Epub 2010 Feb 20.

Mammalian G-protein-coupled receptor expression in Escherichia coli: I. High-throughput large-scale production as inclusion bodies.
Michalke K, Gravière ME, Huyghe C, Vincentelli R, Wagner R, Pattus F, Schroeder K, Oschmann J, Rudolph R, Cambillau C, Desmyter A.
Anal Biochem. 2009 Mar 15;386(2):147-55. Epub 2008 Dec 24.

A novel, generic and effective method for the rapid purification of G protein-coupled receptors.
Magnin Fiez-Vandal C, Potier N, Coquard A, Leray I, Steffan T, Logez C, Alkhalfioui F, Pattus F, Wagner R.
Protein Expr Purif. 2009 Mar;64(1):1-7. Epub 2008 Sep 19.

Structural genomics on membrane proteins: comparison of more than 100 GPCRs in 3 expression systems.
Lundstrom K, Wagner R, Reinhart C, Desmyter A, Cherouati N, Magnin T, Zeder-Lutz G, Courtot M, Prual C, André N, Hassaine G, Michel H, Cambillau C, Pattus F.
J Struct Funct Genomics. 2006 Jun;7(2):77-91. Epub 2006 Nov 22.

Cytobody field :

A focused antibody library for selecting scFvs expressed at high level in the cytoplasm
Pascal Philibert, Etienne Weiss, Pierre Martineau et al.
BMC Biotechnology 2007, 7:81

A novel drug like spleen tyrosine kinase binder prevents anaphylactic shock when administered orally.
Pierre Martineau, Piona Dariavach et al.
The Journal of Allergy and Clinical Immunology (2008) 122: 188-194.